Everyone, I'm late to the party here, but the conversation is arresting nonetheless!
To go back to Suresh's original issue, about emerging companies making it big, and then looking at his last comment about the three issues in his mind now, here is my 2c.
First, I tend to agree that undifferentiated offerings are not a no-no. But investors tend to believe that a defensible differentiation is critical to success - at least in the initial years. VCs take big risks, so a defensible proposition is critical at that stage. But as markets grow, multiple products vie for mind-space, so differentiations move from being truly disruptive to being truly well-branded. In the former case, the customer is buying because you do something better than anyone else; in the latter, because s/he BELIEVES you do. Of course, all this is not sacrosanct, but by and large, products and services tend to evolve (if that's the word) in this manner.
Second, given that markets move in this manner, as an entrepreneur/investor/employee, I need to pick the battles I want to fight. If I enjoy the "rush" of building something new, I look for an emerging space to build/invest/work in. If building something big is what I am after, I look for a space that's more "mature". The challenges are different at either end of the spectrum and so, so are the skills needed.
Therein, I think, lies the most important reason for emerging companies failing to grow - the inability to make the transition from a feisty start-up to a larger, more "inclusive" company.
End 2c!